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Enucleation – Ocular Melanoma Treatment

Surgical removal of the eye, most often reserved for large tumors or when vision cannot be preserved. A conformer is placed at the time of surgery to maintain the shape of the socket, and a prosthetic eye is usually fitted later. In some cases, especially when the tumor has spread beyond the eye, the entire socket and surrounding tissues may also need to be removed.

1

Before Surgery

Decision to Enucleate

  • Enucleation is usually considered when:
    • The tumor is too large for radiation.
    • Vision is already lost or cannot be preserved.
    • There is painful glaucoma or tumor recurrence.
    • There is concern for extraocular extension (tumor growing outside the eye).

Preoperative Counseling

  • You will meet with an ophthalmic oncologist and oculoplastic surgeon.
  • The risks, benefits, and emotional impact will be discussed.
  • You’ll be fitted for a conformer (temporary implant) and later a custom ocular prosthesis.

2

The Procedure

Surgical Steps

  • Performed under general anesthesia (you’ll be asleep).
  • The entire eyeball is carefully removed.
  • Optic nerve is clipped (as close as possible to the globe).
  • A ball-shaped orbital implant (usually made of porous material like hydroxyapatite or silicone) is placed in the eye socket to restore volume.
  • Muscles that controlled the eye are attached to the implant to allow natural movement.

Post-Op Setup

  • A temporary conformer (plastic shell) is inserted to maintain the shape of the socket.
  • The eyelids are partially sewn shut (temporary tarsorrhaphy) to protect healing tissue.
  • The eye is covered with a pressure patch for 1–2 days.

3

Recovery Period

First Few Days

  • Mild pain, swelling, bruising around the eyelids.
  • Medications include antibiotics and pain relievers.
  • The pressure patch is removed within 48 hours; you’ll see swelling and sutures.

Follow-Up Visits

  • You’ll be closely monitored for signs of infection or complications.
  • Stitches dissolve or are removed after a few weeks.

4

Ocular Prosthesis

Fitting the Prosthetic Eye

  • About 6–8 weeks post-surgery (after swelling resolves), you’ll be referred to an ocularist.
  • They’ll craft a custom-made prosthetic eye that matches your other eye in size and color.
  • The prosthesis fits over the implant and under the eyelids.

Movement and Appearance

  • Most modern prostheses move in coordination with the remaining eye.
  • Many people find the cosmetic result quite natural.

5

Risks and Side Effects

Common Short-Term Effects

  • Swelling, bruising, mild bleeding.
  • Temporary eyelid stiffness or discomfort.

Long-Term Risks

  • Implant migration or extrusion (rare with modern materials).
  • Socket infection or inflammation.
  • Dry eye or discharge.

6

Emotional Adjustment

  • Losing an eye is a significant psychological event.
  • Grief, anxiety, or changes in self-image are common.
  • Support groups, counseling, and patient networks like A Cure In Sight can help you cope.
  • Many patients return to regular life—including work, driving (if the other eye has good vision), and sports—after recovery.

7

Prognosis and Monitoring

  • Enucleation often provides excellent local tumor control.
  • Your removed eye is sent for histopathologic analysis to evaluate tumor type, size, cell characteristics, and any extrascleral extension.
  • Ongoing follow-up includes:
    • Orbital exams to check for regrowth.
    • Imaging and systemic monitoring for metastatic disease, especially in the liver.